Challenge-Based Learning (CBL) is increasingly being used as a didactical innovation in health professions education worldwide with the overall aim of supporting learners in their capacity to tackle real-world challenges. Key elements of CBL, next to knowledge enhancement, are competency development & reflection, interprofessional and interdisciplinary collaboration, and community engagement. In the context of health and healthcare, CBL has proven to empowers learners to co-create meaningful solutions with stakeholders, addressing complex medical, social, and systemic issues in real-life healthcare contexts (Tang et al., 2024; Valentijn et al, 2023).